A Study on Exoenzyme Activities of Candida albicans Isolated from Oral Cavities of HIV-Infected Patients on HAART
نویسندگان
چکیده
Morbidity and mortality have decreased significantly since the introduction of highly active anti-retroviral therapy (HAART) for treating HIV-infected patients [1,2]. The decline in the incidence of oro pharyngeal candidiasis is thought to be due to immune reconstitution of the host and HIV-protease inhibitors (HIV-PIs) in HAART. HIV-PI has been shown to exert both in vivo and in vitro effects on Candida species; in particular, the inhibition of secreted aspartyl proteinase (Sap) secretion [3,4].
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